Aims: The presence of a patient with breast cancer in the family can be considered as a guidance for further prevention and increase the susceptibility of people against this disease. Champion's health belief model scale is translated and tested in different countries, but few attempts have been made to measure this scale in women with history of breast cancer. Methods: After the standard Champion's Health Belief Model Scale was translated, 28 items were extracted with the help of panel of experts (n=13) and focus group (n=42) in four subscales. The eligible women were selected randomly (n=200) and took part in this study. The participants filled in the questionnaire through interviews. To test the construct validity of the data, the confirmatory factor analysis (CFA) was applied using AMOS software, moreover, test of internal consistency and test of reliability were applied by retesting (n=30). Findings: The confirmatory factor analysis, which, was repeated after omitting these two items for the subscale of perceived barriers and shows the proper fit of its structural model. Cronbach 'alpha coefficients were 0.72 (susceptibility), 0.75 (seriousness), 0.82 (benefits) and 0.76 (barriers). Internal consistency ranged from 0 .64 to 0 .79 and test-retest reliability correlation were from 0 .67 to 0.92. Conclusions: The Persian version of the Champion's Health Belief Model Scale can be a reliable and valid measure in Iranian women with family history of breast cancer.